Name |
Joaquin Pastor |
Height |
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Naionality |
American |
Date of Birth |
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Place of Birth |
America |
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Joaquín Pastor was born in Madrid in 1964. He graduated from the Universidad de Alcalá in 1987 and obtained his PhD in 1994 working on novel heterocyclic molecules with DNA intercalation properties.
He joined K.C. Nicolaou’s group at the Scripps Research Institute, La Jolla, USA, as a Postdoctoral Fellow until 1998. He worked on projects aimed at the total synthesis of natural products with biological interest, using classical and solid phase based approaches. He co-led a team to develop new solid phase routes and polymer bound reagents in the field of combinatorial chemistry. The significance of this work resulted in a paper published in Nature in 1997, reporting the solid phase synthesis of Epothilones - molecules which are currently in the clinic as anticancer agents.
Pastor was appointed as Head of High Throughput Medicinal Chemistry (HTMC) at Janssen Pharmaceutical, Spain, in 1998. The HTMC Group was a key player in the implementation of Parallel Synthesis Technology and participated actively in projects (oncology and CNS), which produced 2 clinical candidates.
In 2004 he was appointed as Head of the HTMC and Analytical and Purification Technology Groups at Janssen, Belgium, where he was responsible for the design and preparation of chemical libraries - protein kinase inhibitors in particular. He then returned to Spain as Leader of a CNS and the European Lead Generation Groups.
He joined the CNIO as Head of Medicinal Chemistry in the Experimental Therapeutics Programme in June 2008. He is author of more than 35 peer-reviewed articles and patents.